3 edition of DNA methylation, biochemistry, and biological significance found in the catalog.
Includes bibliographies and index.
|Other titles||D.N.A. methylation, biochemistry, and biological significance. V. Series.|
|Statement||edited by Aharon Razin, Howard Cedar, and Arthur D. Riggs ; with contributions by K.F. Conklin ... [et al.].|
|Series||Springer series in molecular biology|
|Contributions||Razin, Aharon, 1935-, Cedar, Howard, 1943-, Riggs, Arthur D.|
|LC Classifications||QP624 .D15 1984|
|The Physical Object|
|Pagination||xiii, 392 p. :|
|Number of Pages||392|
|LC Control Number||84005475|
The biological importance of 5-mC as a major epigenetic modification in phenotype and gene expression has been widely recognized. For example DNA hypomethylation, the decrease in global DNA methylation, is likely caused by methyl-deficiency due to a variety of environmental influences and has been proposed as a molecular marker in multiple biological processes such as cancer. DNA methylation patterns are set up early in mammalian development and are then copied during the division of somatic cells. A long-established model for the maintenance of these patterns explains some, but not all, of the data that is now by:
Table of Contents 1. Introduction.- Introducing DNA Methylation.- Methyl Bases in DNA.- Distribution of Methylated Bases.- 2. DNA Methylation in the Cell.- The Synthetic Reaction.- a Timing of Methylation in Prokaryotes.- b Timing of Methylation in Eukaryotes.- De Novo and Maintenance Methylation.- Demethylation.- Methylation in Isolated Nuclei.-Pages: The establishment of DNA methylation patterns requires de novo methylation that occurs predominantly during early development and gametogenesis in mice. Here we demonstrate that two recently identified DNA methyltransferases, Dnmt3a and Dnmt3b, are essential for de novo methylation and for mouse development. Inactivation of both genes by gene targeting blocks de novo methylation Cited by:
1 Lu I Leicester, UK. Yun Lian is at the Biological NMR Centre, University of DNA Methylation: Molecular Biology and Biological Significance (). Edited by J. P. Jost and H. I? Saluz. Birkhauser Verlag. pp. ISBN SFr /DM By Stephen Musk This book purports â to provide a comprehensive collection of reports on the state of the art in DNA methylationâ and consists of. Although TET1 DNA methylation is a very interesting observation, the study should be extended to a larger group of patients to identify its biological significance and prognostic value. Consistent with our findings, other reports have also indicated the relevance of TET1 promoter DNA methylation in by:
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This item: DNA Methylation: Biochemistry and Biological Significance (Springer Series in Molecular and Cell Biology) Set up a giveaway. Get fast, free delivery with Amazon Prime.
Prime members enjoy FREE Two-Day Delivery and exclusive access to music, movies, TV shows, original audio series, and Kindle : $ It is in the context of this flood of information that this series of monographs on molecular biology has been organized.
The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject Brand: Springer-Verlag New York. Dna Methylation: Molecular Biology And Biological Significance (Experientia Supplementum): Medicine & Health Science Books @ ed by: DNA Methylation Molecular Biology and Biological Significance.
Authors The explosive increase in the number of publications dealing with DNA methylation attests to its importance and makes it impossible to write a comprehensive coverage of the literature within the scope of a general review. DNA Methylation Book Subtitle Molecular.
DNA Methylation ‐ biochemistry and biological significance. Edited by A. Razin, H. Cedar and A. Riggs. Springer‐Verlag, New York, Pp.
Author: Norman Maclean. Book Overview During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In very little was known of the chemical constitution of biological systems, the manner in which information was trans mitted from one organism to another, or the extent to which the chemical basis of life is unified.
Additional Physical Format: Online version: DNA methylation, biochemistry, and biological significance. New York: Springer-Verlag, © (OCoLC) Get this from a library. DNA Methylation: Biochemistry and Biological Significance. [Aharon Razin; Howard Cedar; Arthur D Riggs] -- During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology.
In very little was known of the chemical constitution of biological systems, the. On the Biological Significance of DNA Methylation Article Literature Review (PDF Available) in Biochemistry (Moscow) 70(5) June with 81 Reads How we measure 'reads'.
DNA Methylation: Biochemistry and Biological Significance Springer Series in Molecular and Cell Biology: : Razin, A., Cedar, H., Riggs, A. D., Conklin, K.F Format: Tapa dura.
It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field.
This will enable the reader to get a sense. Steroid hormone-dependent changes in DNA methylation and its significance for the activation or silencing of specific genes.- Epigenetic inheritance based on DNA methylation.- DNA methylation and genomic imprinting in mammals.- DNA methylation and cancer.- The repair of 5-methylcytosine deamination damage.- Gene methylation patterns and expression.
A large number of studies have documented the methylation patterns of individual genes and repeated sequences in different tissues of various mammalian species.
This has revealed a consistent picture of DNA modification where each cell type has its characteristic by: BloodReviews()10, 0PearsonProfessionalLtd State of the art DNA methylation: biology and significance oye,C.S. Davies, The modificationof DNAby cytosinemethylationis crucialfor methylationpatternsare distinctivebetweentissues and are maintainedwithhigh fidelityduringcell Cited by: Book Reviews Biochemistry and Biology of DNA Methylation Edited by Giulio L.
Cantoni and Aharon Razin Alan R. Liss; New York, xv + pages. E This book, Vol. in the series ‘Progress in Clinical and Biological Research’, represents the Proceedings. The state of the art of DNA methylation research is considered in this multi-author book. The volume comprises 24 chapters which cover the history of DNA methylation research, DNA methylation and DNA binding proteins, genome imprinting, DNA methylation and gene expression regulation and the role of DNA methylation in cancer.
A subject index is provided. SIGNIFICANCE OF DNA METHYLATION BIOCHEMISTRY (Moscow) Vol. 70 No. 5 complementary strand of DNA. Conversely, the fixation of de novomethylation patterns on integrated foreign DNA or in the course of embryonic development might be directed by local chromatin structures, which then would have to be ﬁrememberedﬂ even in the absence of.
DNA methylation is an epigenetic mark that is involved in control mechanisms of a variety of biological processes. Being symmetrically positioned on the two comple-mentary DNA strands the methyl. DNA methylation is necessary for proper embryonic development, as mice lacking any functional DNA methyltransferase gene fail to develop properly and die in midgestation.
It has been suggested that methylation is a novel repression mechanism developed in more complex organisms to reduce ‘transcriptional noise’  — the inappropriate Cited by: Evidence for the absence of biological methylation of lead in the environment.
Nature(), DOI: /a0. Wainwright. Mineral transformations by fungi in. Biological methylation occurs in various ways. In epigenetic inheritance, methylation can occur as DNA methylation or protein methylation. In DNA methylation, there is an addition of a methyl group to a cytosine residue, causing cytosine to become 5-methylcytosine.
DNA methylation. DNA methylation is an epigenetic modification of DNA that is important for the normal regulation of transcription, embryonic development, genomic Cited by: DNA methylation is essential for the development of mammals (1, 2), but despite 25 years of work, researchers still do not know exactly advances have led to the cloning and preliminary characterization of the three known active DNA cytosine methyltransferases (DNMT1, -3a, and -3b) (3,4) and to a greater understanding of how the methylation signal is interpreted in Cited by: